Spherical silica nanoparticles promote malignant transformation of BEAS-2B cells by stromal cell-derived factor-1α (SDF-1α)
نویسندگان
چکیده
منابع مشابه
Involvement of matrix metalloproteinase-13 in stromal-cell-derived factor- 1α(SDF-1α)-induced invasion of human basal cell carcinoma cells
Department of Dermatology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan; Angiogenesis Research Center, Laboratory of Molecular and Cellular Toxicology, Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan; Departments of Pathology and Otolaryngology, National Taiwan University Hospital and National Tai...
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BACKGROUND Activated cardiac fibroblasts (CFs), preglomerular vascular smooth muscle cells (PGVSMCs), and glomerular mesangial cells (GMCs) proliferate, cause hypertrophy, and produce collagen; in this way, activated CFs contribute to cardiac fibrosis, and activated PGVSMCs and GMCs promote renal fibrosis. In heart and kidney diseases, SDF-1α (stromal cell-derived factor 1α; endogenous CXCR4 [C...
متن کاملEpigenetic Regulation of Cardiac Progenitor Cells Marker c-kit by Stromal Cell Derived Factor-1α
BACKGROUND Cardiac progenitor cells (CPCs) have been proven suitable for stem cell therapy after myocardial infarction, especially c-kit(+)CPCs. CPCs marker c-kit and its ligand, the stem cell factor (SCF), are linked as c-kit/SCF axis, which is associated with the functions of proliferation and differentiation. In our previous study, we found that stromal cell-derived factor-1α (SDF-1α) could ...
متن کاملexpression of stromal derived factor alpha (sdf-1α) by primary hepatocytes following isolation and heat shock stimulation
stromal derived factor-a (sdf-1-a) is a cxc chemokine which has been demonstrated as a recruitment factor for leukocytes to the site of inflammation, infection, injury and following stress. this chemokine has been shown to be expressed by liver cells and in liver diseases. hence, the aim of this study was to examine the expression of sdf-1 by hepatocytes in responses to the stress imposed durin...
متن کاملStromal Cell-Derived Factor 1α Induces Accumulation of Intraveneously Administered Marrow-Derived Stromal Cells in the Partially Obstructed Rat Bladder.
OBJECTIVES We investigated the time course of the stromal cell-derived factor 1α (SDF1α) expression and behavior of intravenously administered bone marrow-derived stromal (BMS) cells in the urinary bladder of partial bladder outlet obstruction (PBOO) rats. METHODS Study 1: Recombinant SDF1α or saline was directly injected into the bladder wall of female rats followed by intravenous administra...
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ژورنال
عنوان ژورنال: Journal of International Medical Research
سال: 2019
ISSN: 0300-0605,1473-2300
DOI: 10.1177/0300060518814333